Polynucleotides
Polynucleotides are sometimes referred to as Skin Boosters but they do more than that. These bio-stimulatory injectables support your skin's own repair pathways, stimulating fibroblasts to produce collagen and elastin, improving hydration, and providing antioxidant benefits. Results build gradually and look natural.
A new frontier in aesthetic medicine, gaining popularity for their unique ability to stimulate natural skin regeneration with minimal risk and compatibility with other injectable treatments.
What are polynucleotides?
Polynucleotides are long chains of DNA, typically derived from salmon or trout sperm and highly purified and suspended in water to be available as an injectable. Different brands offer varying concentrations of these highly purified polynucleotides (PN-HPT).
At ELEVOskin, I've carefully evaluated available options and selected those with the highest concentration and most proven benefits for my patients. I also offer a hybrid formulation combining Polynucleotides and Hyaluronic Acid for enhanced skin hydration and plumping effects for those with more static deep lines.
What do polynucleotides help with?
The natural process of skin ageing isn't limited to fine lines or sagging, it's a complex cellular process that gradually reduces the skin's ability to regenerate, repair, and retain moisture. Polynucleotides work through several mechanisms:
Stimulation of Fibroblasts
Activate fibroblasts responsible for producing collagen, elastin, and hyaluronic acid, helping preserve or restore skin thickness and bounce.
Cellular Support
Provide building blocks for DNA and RNA synthesis, delivering raw materials and building blocks for repair and regeneration.
Hydration & Water Retention
Due to their hydrophilic structure, they attract and retain water, contributing to subtle plumping and improved texture.
Anti-Inflammatory Effects
Modulate immune responses by reducing pro-inflammatory activity, helping calm reactive, red or irritated skin.
Antioxidant Action
Function as antioxidants, scavenging free radicals that damage skin cells and break down collagen and elastin.
Wound Healing & Repair
Signal intensive repair, improving scars, stretch marks, uneven texture improving overall skin health
We will start with a detailed consultation to understand your skin's needs and develop a personalised treatment plan. Treatment entails 30-35 minute sessions using fine needles or cannula with numbing cream beforehand for comfort.
Depending on product used, downtime varies but mild swelling/redness resolving within 3-5 hours is common so do plan accordingly around your events. Bruising can be common with this treatment which can last up to14 days. A course of 3 sessions is recommended for optimal results. Benefits typically last up to six months, with 6-8 monthly maintenance sessions recommended.

